TCRN Practice Exam 2025 – Complete Prep for Your Test

In the context of treating patients who have experienced a subarachnoid hemorrhage, calcium channel blockers are particularly vital in the prevention and management of vasospasms. After a subarachnoid hemorrhage occurs, the risk of vasospasms—narrowing of blood vessels that can reduce blood flow to the brain—significantly increases. This can lead to ischemia and further complications, making it critical to mitigate this risk.

Calcium channel blockers, such as nimodipine, specifically target cerebral vasospasm. These medications work by inhibiting calcium entry into vascular smooth muscle, thereby promoting vasodilation and preventing the contraction of blood vessel walls. This action is crucial in maintaining optimal cerebral blood flow during the critical period following a subarachnoid hemorrhage.

Other medications listed, such as beta-blockers, direct vasodilators, and ACE inhibitors, do not have the same efficacy in preventing vasospasm specifically related to subarachnoid hemorrhage. They may have other roles in cardiovascular management but lack the targeted action required to protect against vasospasm in this specific neurological context.